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LouDiamond

Feeling Hypoxic? Inhale this drug......

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Well not quite yet, but DARPA is working on it. Read more about how DARPA is working on developing an inhaled drug to increase performance for troops at high altitudes. Read about it HERE


The potential trickle down from this could potentially be seen on DZ's one day in the future, who knows.
"It's just skydiving..additional drama is not required"
Some people dream about flying, I live my dream
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What, synthesising oxygen?

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That’s an adaptive process the human body is already capable of, but the necessary acclimatization can take weeks. Dr. Jonathan Stamler, who’s leading the research at Case Western, says the drugs will essentially do what we already can.

“We’re essentially mimicking nature here,” he tells Danger Room. “Take people climbing mountains, who will set up base camps at varying altitudes to give their bodies time to adjust. We’re making these mechanisms much, much more acute — a matter of minutes, rather than days.”



If you can carry enough oxygen you do not need to aclimatise, no?
"When the power of love overcomes the love of power, then the world will see peace." - 'Jimi' Hendrix

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A long time ago a friend and climbing partner got his hands on some Diamox. It is given to climbers/patients up on Everest and the likes to increase oxygen absorbtion. We had planned a night on the summit of Mt Whitney, 14,505', so he took a dose. He ended up spending almost the entire night running in place, doing jumping jacks, pacing, etc. He said that stuff was real powerful and would never touch it again. He better not cuz I was gonna brain him if he kept me up like that again!

jon

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Well, the government invented Meth...so why not trust them ?:S

BUT, all jokes aside...I see new world skydiving records :)



meth was originally invented by the GERMANS.. ;)

WRONG... The Germans first commercialised it in 1938.. But a japanese (Akira Ogata) synthesized it first in 1919 (according to wikipedia)
scissors beat paper, paper beat rock, rock beat wingsuit - KarlM

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Well, the government invented Meth...so why not trust them ?:S

BUT, all jokes aside...I see new world skydiving records :)



meth was originally invented by the GERMANS.. ;)

WRONG... The Germans first commercialised it in 1938.. But a japanese (Akira Ogata) synthesized it first in 1919 (according to wikipedia)



fair enough; i was thinking about the commercialising.. :)
“Some may never live, but the crazy never die.”
-Hunter S. Thompson
"No. Try not. Do... or do not. There is no try."
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A long time ago a friend and climbing partner got his hands on some Diamox. It is given to climbers/patients up on Everest and the likes to increase oxygen absorbtion. We had planned a night on the summit of Mt Whitney, 14,505', so he took a dose. He ended up spending almost the entire night running in place, doing jumping jacks, pacing, etc. He said that stuff was real powerful and would never touch it again. He better not cuz I was gonna brain him if he kept me up like that again!

jon


Sounds like just a dosage issue. I would be curious to know what the back side of the episode is like. This would be particularly important on a long campaign like Everest, or a week long bigway record attempt.

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Sounds like just a dosage issue. I would be curious to know what the back side of the episode is like. This would be particularly important on a long campaign like Everest, or a week long bigway record attempt.



He was a pathologist in LA who got a doc friend to write him a scrip. No dosage instructions as the doc didn't know any more than my buddy. Funny now but he was pretty un-nerved at the time and had a miserable night and day after.

jon

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Well, the government invented Meth...so why not trust them ?:S

BUT, all jokes aside...I see new world skydiving records :)



meth was originally invented by the GERMANS.. ;)

WRONG... The Germans first commercialised it in 1938.. But a japanese (Akira Ogata) synthesized it first in 1919 (according to wikipedia)



Ah! Speaking of the Axis, the Italians did NOT invent spaghetti.

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Hypoxia is caused by a reduction in ambient pressure. I can’t see where inhaling a drug is going to increase that pressure allowing exchange of O2/CO2.

Sparky



Change the chemical/molecular structure of those cells that exchange oxygen and CO2 and maybe it'll happen more readily at lower pressures. Is that their thinking? Or is there another compound/chemical one can take to enhance that ability?

jon

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records say US army!

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Methamphetamine was first synthesized from ephedrine in Japan in 1893 by chemist Nagai Nagayoshi.[8] In 1919, crystallized methamphetamine was synthesized by Akira Ogata via reduction of ephedrine using red phosphorus and iodine. In 1943, Abbott Laboratories requested for its approval from the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, mild depression, postencephalitic parkinsonism, chronic alcoholism, cerebral arteriosclerosis, and hay fever. Methamphetamine was approved for all of these indications in December, 1944. All of these indication approvals were eventually removed[9]

from en.wikipedia.org/wiki/Methamphetamine
scissors beat paper, paper beat rock, rock beat wingsuit - KarlM

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Hypoxia is caused by a reduction in ambient pressure. I can’t see where inhaling a drug is going to increase that pressure allowing exchange of O2/CO2.

Sparky




Did you read the article I linked to? It explains how they hope to achieve this.
"It's just skydiving..additional drama is not required"
Some people dream about flying, I live my dream
SKYMONKEY PUBLISHING

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>Hypoxia is caused by a reduction in ambient pressure.

It's actually caused by a failure to deliver enough oxygen to your tissues. It can be caused by:

-restricted blood supply
-lower atmospheric pressure
-higher pressure but lower ppO2 (i.e. exotic dive mixes)
-medical problems (low hemoglobin count)
-changes in blood pH
-problems with gas exchange in your lungs

You can't increase the ppO2 your lungs get with a drug - but you can definitely affect the rest of the above via medical interventions.

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>Hypoxia is caused by a reduction in ambient pressure.

It's actually caused by a failure to deliver enough oxygen to your tissues. It can be caused by:

-restricted blood supply
-lower atmospheric pressure
-higher pressure but lower ppO2 (i.e. exotic dive mixes)
-medical problems (low hemoglobin count)
-changes in blood pH
-problems with gas exchange in your lungs

You can't increase the ppO2 your lungs get with a drug - but you can definitely affect the rest of the above via medical interventions.



Actually there are 4 types of hypoxia. The one skydivers would be confronted with is #1 Hypoxic hypoxia. And that is caused by reduced pressure.


1. Hypoxic hypoxia results from an inadequate oxygenation of the arterial blood and is
caused by reduced oxygen partial pressure.

2. Anemic hypoxia results from the reduced oxygen- carrying capacity of the blood, which
may be due to blood loss, any of the anemias, carbon monoxide poisoning, or by drugs
causing methemogiobinemia.

3. Stagnant hypoxia is caused by a circulatory malfunction which results, for example, from the venous pooling encountered during acceleration maneuvers.

4. Histofoxic hypoxia results from an inability of the cells to utilize the oxygen provided
when the normal oxidation processes have been poisoned such as by cyanide. There is no oxygen lack in the tissues, but rather an inability to use available oxygen, with the result that the PO2 in the tissues may be higher than normal. Therefore, it is not true hypoxia by the definition used here.

Source: US Navy Flight Surgeons Manual


Sparky
My idea of a fair fight is clubbing baby seals

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Sounds like just a dosage issue. I would be curious to know what the back side of the episode is like. This would be particularly important on a long campaign like Everest, or a week long bigway record attempt.



He was a pathologist in LA who got a doc friend to write him a scrip. No dosage instructions as the doc didn't know any more than my buddy. Funny now but he was pretty un-nerved at the time and had a miserable night and day after.

jon



diamox is the sh*t when it comes to acclimatization. it doesn't replace it, but rather speeds it up by changing your blood chemistry (acidity). last may i went to north col of mnt. Everest and spend a night at 23k+ and diamox was a good help. the side effects - peeing more and beer doesn't taste very good. but it beats feeling like crap at the alti

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it's not about defying gravity; it's how hard you can abuse it. speed skydiving it is ...
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